Institut Pasteur de Dakar (IPD) : First-Of-Its-Kind Vaccine Manufacturing Facility to Africa
Driving self-sustaining COVID-19 vaccine solutions in Africa
Our team at KeyPlants, together with a group of international companies, funders, and governments, have designed and built a first-of-its-kind vaccine manufacturing filling facility in Senegal, Africa. Project MADIBA leverages our unmatched expertise and vast experience in modular solutions and off-site manufacturing to develop this transformative facility in under a year. Owned and managed by Institut Pasteur de Dakar (IPD), the facility will revolutionize access to vaccines in Africa.
What can the Project MADIBA facility achieve?
This facility has the capacity to produce 300 million COVID-19 vaccine doses annually. Its multi-suite drug substance and fill-finish capabilities also mean it has the flexibility to facilitate processes across the pharmaceutical and biomanufacturing industries, beyond mRNA vaccine manufacturing. As a result, it can enable rapid vaccination of the Senegalese population and neighboring countries against COVID-19, while offering the flexibility to meet changing pandemic and global health needs. The portable and prefabricated design of the facility also allows for a rapid and low-risk scale-up or scale-out process to meet evolving needs of the local community.
Project MADIBA’s mission
This pioneering project aims to implement a self-sustaining and reactive vaccination infrastructure in Africa, taking the first step towards the continent’s goal of vaccine autonomy. It will serve as a blueprint for future vaccine manufacturing facilities to be built across Africa. With off-site construction reducing risk and eliminating the need for complex assembly logistics on site, this project serves to highlight that anywhere in the world can now have access to crucial biomanufacturing facilities to produce life-saving medicines.
Through the MADIBA project, the Institute Pasteur of Dakar and its partners are responding to the COVID-19 pandemic by achieving equitable access to life-saving vaccines for Africans. KeyPlants has contributed crucial experience in off-site module manufacturing, enabling us to open an innovative manufacturing facility in Senegal in record time.
Project MADIBA’s Journey
1. Design
The facility’s design draws upon our vast experience in the industry and our extensive portfolio of previous projects, as well as the need to meet stringent regulatory standards.
2. Procurement
During this phase, our specialized team at KeyPlants handle complex procurement interactions with vendors and integrate elaborate process equipment systems
3. Manufacturing
By choosing off-site construction, there is the opportunity to apply sustainable and controlled practices in a safe environment, ensuring the highest regulatory and sanitary standards are maintained.
4. Construction
While KeyPlants design and build the facility off site, IPD prepare the site, build the foundation, and construct the shell building in parallel. This saves time further down the line.
Next Steps in Project MADIBA’s journey
Now, vaccine manufacturing can begin!
Our first-of-its-kind facility being shipped from the workshop in Sweden, on its way to Senegal.
Facility in focus
The Project MADIBA facility is a filling facility capable of filling both vials and pouches due to the use of MEDInstill’s novel INTACT™ pouch technology. The pouch connects to its multi-use injector which will deliver 200 doses of the COVID-19 vaccine to patients without losing container closure integrity and having zero exposure to critical surfaces, while an individual needle for each patient prevents any risk of cross-contamination between patients. Thus, the facility is able to achieve improved high-throughput vaccine manufacturing capabilities safely.
Daniel Py, CEO and Founder of MEDInstill says “With the adoption of MEDInstill’s technology, Project MADIBA will be both transformative and disruptive in the Pharma and Biopharma space by delivering vaccines to those in need at an unmatched safety level.”
Also, the simplified procurement process and prefabricated design of the facility means it is easily reproducible. It therefore provides a safe, rapid and scalable solution to meet biomanufacturing needs.
Watch our video to learn more about the facility, developed as part of Project MADIBA and in collaboration with the Institut Pasteur de Dakar (IPD) and Medinstill.
Expert on-site construction team, Senegal
Mechanical floor
Section of production floor
Manufactured facility in workshop, Sweden
Facility in preparation for shipping
Lamine Sene, Head of Infrastructure, IPD | Hans Davidsson, Project Director, KeyPlants
KeyPlants, a leading provider of innovative life science facilities
KeyPlants was chosen to execute the ambitious goal of Project MADIBA due to our unrivalled experience in successfully designing, manufacturing, delivering, and commissioning over 4,500 off-site modules to customers worldwide. The controlled production environment means that safety always comes first for us.
In combination with our vast understanding of the industry and integrated supply chain control, this positions KeyPlants as a reliable partner who can mitigate project risks and meet tailored biomanufacturing needs in short and predictable timelines. At KeyPlants we provide turnkey solutions, no matter the scale of the project, to ensure drugs reach patients faster.
KeyPlants is part of Masco Group, a family of companies that deliver integrated projects to support its customers manufacturing in the pharmaceutical and biopharmaceutical space.
Contact us to discover how our expert team can provide a modular solution tailored to your biomanufacturing projects.
Delivering Excellence For Your Projects
To find out how the team at KeyPlants can help with your project goals, please drop us an email today.